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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP5
All Species:
35.45
Human Site:
S53
Identified Species:
55.71
UniProt:
Q8N3R9
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3R9
NP_071919.2
675
77294
S53
R
M
M
P
I
R
R
S
A
Q
L
E
R
I
R
Chimpanzee
Pan troglodytes
XP_510014
764
85553
S142
R
M
M
P
I
R
R
S
A
Q
L
E
R
I
R
Rhesus Macaque
Macaca mulatta
XP_001105724
674
77301
S53
R
M
M
P
I
R
R
S
A
Q
L
E
R
I
R
Dog
Lupus familis
XP_547862
675
77214
S53
R
M
M
P
V
R
R
S
A
Q
L
E
R
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLB2
675
77211
S53
R
M
M
P
V
R
R
S
A
Q
L
E
R
I
R
Rat
Rattus norvegicus
Q5U2Y3
576
65604
H48
M
F
G
E
K
S
L
H
S
L
V
K
I
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505475
675
76860
S53
R
M
M
P
I
R
R
S
A
Q
L
E
R
I
R
Chicken
Gallus gallus
Q5ZJ00
468
52501
Frog
Xenopus laevis
NP_001085267
675
76810
S53
R
A
M
P
I
R
R
S
A
Q
L
E
R
I
R
Zebra Danio
Brachydanio rerio
Q8JHF4
677
76390
S50
R
T
L
P
V
R
R
S
A
Q
L
E
K
I
R
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
Fruit Fly
Dros. melanogaster
Q24210
898
100893
S216
V
M
L
H
V
L
L
S
G
R
L
P
F
L
G
Honey Bee
Apis mellifera
XP_393395
1033
115664
S382
L
N
R
S
L
R
G
S
K
K
L
Q
A
L
E
Nematode Worm
Caenorhab. elegans
P54936
961
108794
H76
R
I
C
Q
N
L
Q
H
P
Y
I
C
R
L
E
Sea Urchin
Strong. purpuratus
XP_784409
971
107892
K91
R
T
I
N
L
R
V
K
R
R
T
I
R
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.6
97
98.2
N.A.
96.7
36.2
N.A.
93.7
25
86
77
25.7
26.7
34.7
24.1
34.7
Protein Similarity:
100
87.5
97.7
99.5
N.A.
98.6
54.9
N.A.
96.8
43.8
92.5
86.7
44.5
46.3
49.2
41.7
49.2
P-Site Identity:
100
100
100
93.3
N.A.
93.3
0
N.A.
100
0
93.3
73.3
0
20
20
13.3
20
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
100
0
93.3
93.3
0
46.6
46.6
40
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
0
54
0
0
0
7
0
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% D
% Glu:
0
0
0
7
0
0
0
0
0
0
0
54
0
0
20
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
7
0
0
0
7
0
7
0
0
0
0
0
14
% G
% His:
0
0
0
7
0
0
0
14
0
0
0
0
0
7
0
% H
% Ile:
0
7
7
0
34
0
0
0
0
0
7
7
7
54
0
% I
% Lys:
0
0
0
0
7
0
0
7
7
7
0
7
7
0
0
% K
% Leu:
7
0
14
0
14
14
14
0
0
7
67
0
0
20
0
% L
% Met:
7
47
47
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
7
7
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
54
0
0
0
0
7
0
0
7
0
0
0
% P
% Gln:
0
0
0
7
0
0
7
0
0
54
0
7
0
0
0
% Q
% Arg:
67
0
7
0
0
67
54
0
7
14
0
0
60
0
54
% R
% Ser:
0
0
0
7
0
7
0
67
7
0
0
0
0
0
0
% S
% Thr:
0
14
0
0
0
0
0
0
0
0
7
0
0
0
0
% T
% Val:
7
0
0
0
27
0
7
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _